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所在位置:所有产品 > 抗体抗原 > 一抗 > LDLR抗体
LDLR抗体图片
产品货号:
Z19942
中文名称:
LDLR抗体
英文名称:
Anti-LDLR Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-LDLR Antibody
指标别名FH;FHC;LDL receptor;LDLR
克隆性Polyclonal
检验物种human,mouse,rat
应用范围ELISA,WB,IHC,IF
基因名称LDLR
抗体来源Chicken
抗体类型IgY
免疫原LDL-R antibody was raised against an 18 amino acid synthetic peptide near the center of human LDL-R.The immunogen is located within amino acids 490 - 540 of LDL-R.
计算分子量95kDa
成分LDL-R Antibody is supplied in PBS containing 0.02% sodium azide.
纯化方式LDL-R Antibody is affinity chromatography purified via peptide column.
浓度1mg/mL
产品形态溶液
保存条件4℃可保存3个月,-20℃可保存1年。
背景资料The low density lipoprotein receptor (LDL-R) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands.Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase,the rate-limiting step in cholesterol synthesis.At the same time,a reciprocal stimulation of cholesterol ester synthesis takes place.Mutations in the LDL-R gene cause the autosomal dominant disorder,familial hypercholesterolemia.Along with SCARB1,CLDN1,and the tetraspanin superfamily member CD81,LDL-R has been reported to be an entry factor for the Hepatitis C virus.At least three isoforms of LDL-R are known to exist.
Uniprot IDP01130
基因名全称Low density lipoprotein receptor
蛋白名全称Low density lipoprotein receptor
推荐稀释比LDL-R antibody can be used for detection of LDL-R by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested.

相关搜索:LDLR抗体LDLR多抗Anti-LDLR Antibody
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