产品货号:
Z19942
中文名称:
LDLR抗体
英文名称:
Anti-LDLR Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-LDLR Antibody |
指标别名 | FH;FHC;LDL receptor;LDLR |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | LDLR |
抗体来源 | Chicken |
抗体类型 | IgY |
免疫原 | LDL-R antibody was raised against an 18 amino acid synthetic peptide near the center of human LDL-R.The immunogen is located within amino acids 490 - 540 of LDL-R. |
计算分子量 | 95kDa |
成分 | LDL-R Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | LDL-R Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The low density lipoprotein receptor (LDL-R) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands.Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase,the rate-limiting step in cholesterol synthesis.At the same time,a reciprocal stimulation of cholesterol ester synthesis takes place.Mutations in the LDL-R gene cause the autosomal dominant disorder,familial hypercholesterolemia.Along with SCARB1,CLDN1,and the tetraspanin superfamily member CD81,LDL-R has been reported to be an entry factor for the Hepatitis C virus.At least three isoforms of LDL-R are known to exist. |
Uniprot ID | P01130 |
基因名全称 | Low density lipoprotein receptor |
蛋白名全称 | Low density lipoprotein receptor |
推荐稀释比 | LDL-R antibody can be used for detection of LDL-R by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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